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1.
Clin Nephrol Case Stud ; 11: 35-38, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-36896138

RESUMO

Agromyces mediolanus is a catalase-positive gram-positive rod typically found in the soil and not commonly known to be pathogenic. We present a rare case of Agromyces mediolanus bacteremia with aortic valve endocarditis in a patient who required prolonged inpatient care with a tunneled dialysis catheter for renal replacement therapy (RRT). Infection is the second leading cause of mortality among patients with end-stage renal disease and vascular access. The incidence of bacteremia is higher in patients with indwelling tunneled catheters than in those with an arteriovenous fistula or graft. The most critical risk factor is its prolonged use. Anticipation of the need for long-term definitive renal replacement therapy and planning for the best approach is crucial in preventing catheter-related bloodstream infections (CRBSIs). Human infections caused by Agromyces mediolanus are rare; it has been reported twice, and both cases were associated with prolonged use of catheters, not only parenteral catheter but also peritoneal catheter, which is of special importance for patients with end-stage renal disease (ESRD). Limited data is available for the appropriate antibiotic therapy.

2.
Nurs Open ; 10(3): 1611-1618, 2023 03.
Artigo em Inglês | MEDLINE | ID: mdl-36266761

RESUMO

AIM: To evaluate the impact of an educational intervention focused on teaching students to create infographics to improve pharmacology learning. DESIGN: This is a comparative study. METHODS: The population was 250 nursing students who had to create two infographics in groups related to the content that had been addressed in pharmacology in two different moments. Students and professors evaluated the infographics through a 5-point Likert scale. Scores from the official exam of the pharmacology subject were obtained. RESULTS: Most of the students scored below 50% for the "excellent" and "good" categories. Intraclass correlation and kappa correlations among students and professors' evaluations were low. The comparison between both times of students' evaluations only yields significant correlation values for the criterion "Understanding of information" (r = .039, p = .024) and the "Visual presentation of information" (r = .041, p = .019). No correlation was obtained between the test and evaluations values of the infographic.


Assuntos
Visualização de Dados , Estudantes de Enfermagem , Humanos , Avaliação Educacional , Aprendizagem , Currículo
3.
Cureus ; 12(11): e11674, 2020 Nov 24.
Artigo em Inglês | MEDLINE | ID: mdl-33391911

RESUMO

Daptomycin is a lipopeptide antibiotic that is active against vancomycin-resistant enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). It is less nephrotoxic than vancomycin. It has a unique bactericidal mechanism through destruction of bacterial membrane potential. However, one of the most clinically relevant adverse effects of daptomycin is reversible myopathy, especially when daptomycin is used in high doses. Here, we present a case of a patient with rhabdomyolysis preceded by hyperkalemia associated with daptomycin use. Soon after daptomycin administration, hyperkalemia was noticed before the acute rise in creatinine phosphokinase (CPK). The serum levels of potassium and CPK returned to normal after daptomycin was stopped which suggested the causal relationship between hyperkalemia and myopathy and daptomycin use. To our knowledge, this is the second case of hyperkalemia related to daptomycin use.

4.
Cureus ; 12(12): e11841, 2020 Dec 02.
Artigo em Inglês | MEDLINE | ID: mdl-33409080

RESUMO

Hyponatremia in diabetic ketoacidosis (DKA) is common and can be due to several reasons. However, hypernatremia in DKA is rare and can be life-threatening. Its exact etiology is not clear and several mechanisms related to water deficit from inadequate oral intake and free water loss that supersedes the electrolyte loss through diarrhea or vomiting have been proposed. Treating the DKA more aggressively than the hypernatremia itself, choosing a hypoosmolar fluid, and switching to D5-0.45% saline, when glucose has decreased, are some of the vital considerations for the management of hypernatremia in DKA. We present a 44-year-old male patient with an unclear history of DKA with unusually severe hypernatremia that gradually responded to aggressive management of DKA with rigorous IV hydration and the above-mentioned strategies.

5.
Arch Dis Child ; 101(4): 371-6, 2016 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-26819267

RESUMO

AIM: To investigate the frequency and characteristics of adverse drug reactions (ADRs) in hospitalised neonates to obtain a better understanding of and improvement in neonatal healthcare. METHODOLOGY: A prospective cohort study. Data were collected on 313 neonates and 2166 drug prescriptions. Clinical characteristics of patients, drugs administered and ADRs were prospectively recorded and analysed. Informed consent was obtained in all cases. RESULTS: 116 different ADRs were detected. 17% of the neonates experienced at least one of these ADRs. Systemic antimicrobials and caffeine citrate were the drugs that most commonly caused ADRs. According to the ADR Severity Assessment Scale, 41% were mild, 42% were moderate and 17% were severe. Of the ADRs identified, 11% were classified as 'certain' by the Naranjo method and 20% were classified as 'defined' by the Karch and Lasagna modified algorithm. Most of the ADRs detected were related to feed intolerance, phlebitis and tachycardia. Most were acute (73%) and lasted between 1 and 7 days (39%). After the occurrence of an ADR, it was necessary to initiate specific treatment in 44 cases, discontinue the drugs involved in 30 cases, and reduce the drug dose in another 30 cases. An association was shown between the number of drugs prescribed and ADR onset. CONCLUSIONS: There is a high incidence of ADRs in hospitalised newborns, which increases with the number of prescriptions.


Assuntos
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/epidemiologia , Sistemas de Notificação de Reações Adversas a Medicamentos , Estudos de Coortes , Feminino , Seguimentos , Hospitalização/estatística & dados numéricos , Humanos , Incidência , Recém-Nascido , Masculino , Estudos Prospectivos
7.
Int Sch Res Notices ; 2014: 653045, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-27433484

RESUMO

Cardiovascular disease is the leading cause of morbidity and mortality in the adult population worldwide, with atherosclerosis being its key pathophysiologic component. Atherosclerosis possesses a fundamental chronic inflammatory aspect, and the involvement of numerous inflammatory molecules has been studied in this scenario, particularly C-reactive protein (CRP). CRP is a plasma protein with strong phylogenetic conservation and high resistance to proteolysis, predominantly synthesized in the liver in response to proinflammatory cytokines, especially IL-6, IL-1ß, and TNF. CRP may intervene in atherosclerosis by directly activating the complement system and inducing apoptosis, vascular cell activation, monocyte recruitment, lipid accumulation, and thrombosis, among other actions. Moreover, CRP can dissociate in peripheral tissue-including atheromatous plaques-from its native pentameric form into a monomeric form, which may also be synthesized de novo in extrahepatic sites. Each form exhibits distinct affinities for ligands and receptors, and exerts different effects in the progression of atherosclerosis. In view of epidemiologic evidence associating high CRP levels with cardiovascular risk-reflecting the biologic impact it bears on atherosclerosis-measurement of serum levels of high-sensitivity CRP has been proposed as a tool for assessment of cardiovascular risk.

8.
Arch. boliv. hist. med ; 11(1/2): 30-42, ene.-dic. 2005.
Artigo em Espanhol | LILACS, MOSAICO - Saúde integrativa | ID: lil-487674

RESUMO

Todos los profesionales en salud de los centros poblados del altiplano, ciudades y especialmente centros mineros situados en la cordillera, intuyen la necesidad de un conocimiento, asi sea básico, de los procesos normales y patológicos en los que influye la menor presión de oxígeno ambiental, (PIO2), sobre los sistemas del organismo humano.


Assuntos
Humanos , Masculino , Feminino , Doença da Altitude/enfermagem , Doença da Altitude/história , Bolívia
9.
10.
Apuntes psicol ; 19(2): 207-234, sept. 2001. tab
Artigo em Es | IBECS | ID: ibc-20767

RESUMO

Durante los últimos años han sido numerosas las investigaciones realizadas en nuestro país sobre las denominadas nuevas formas de racismo. Estos trabajos parten de la tendencia que parece existir en la actualidad a expresar el prejuicio étnico de un modo más sutil y menos extremo que en épocas pasadas. Racismo sutil, racismo moderno y racismo simbólico son algunos de los términos que se han acuñado recientemente para hablar de prejuicio étnico. La mayor parte de estas investigaciones recurren a la metodología cuantitativa, empleando traducciones de cuestionarios desarrollados en otros países. Sin embargo, apenas existen trabajos que analicen la realidad del nuevo racismo a través de técnicas de investigación de naturaleza cualitativa. Dada la novedad de este fenómeno y el carácter eminentemente social del prejuicio, se propone la técnica del grupo de discusión como herramienta adecuada para el estudio de las actitudes raciales. En el presente artículo se describen los resultados obtenidos mediante la aplicación de esta metodología, señalando los distintos modos en los que se expresan las actitudes hacia los inmigrantes en nuestro particular contexto social. Para conseguir este objetivo, se combina la técnica del análisis de contenido con el análisis cualitativo de los discursos (AU)


Assuntos
Adolescente , Adulto , Feminino , Masculino , Pessoa de Meia-Idade , Humanos , Preconceito , Problemas Sociais/tendências , Migrantes , Emigração e Imigração/estatística & dados numéricos , Espanha , 25783 , Coleta de Dados/métodos
11.
Psicol. educ. (Madr.) ; 6(1): 27-50, mayo 2000. tab
Artigo em Es | IBECS | ID: ibc-10783

RESUMO

La evaluación del profesorado a través de la encuesta de opinión a los estudiantes ha sido el método más comúnmente utilizado para determinar las características que definen la calidad docente. Sin embargo no existen trabajos, en la literatura previa sobre el tema, que hagan uso del Diferencial Semántico (DS) para dicho fin. El DS permite, además de la detección de los atributos del "profesor ideal", descubrir los componentes evaluativos, emocionales o afectivos ligados a dicho concepto. En el presente trabajo, se pretende descubrir la estructura factorial de la escala utilizada, lo que nos permitirá poner a prueba la hipótesis de la existencia de los factores EPA, tradicionalmente hallados en otras investigaciones con diferentes objetos de actitud. La extracción de las dimensiones más relevantes del profesor de calidad muestra perfiles similares para los distintos grupos considerados y semejantes también a las obtenidas con otros instrumentos de evaluación. Esto confirma, en gran medida, la adecuación del instrumento de evaluación utilizado al fin perseguido con esta investigación (AU)


Assuntos
Adulto , Feminino , Masculino , Pessoa de Meia-Idade , Humanos , Estudantes/psicologia , Atitude , Diferencial Semântico/normas , Psicologia Educacional/métodos , Análise de Variância , Psicometria/métodos , Serviços de Integração Docente-Assistencial/tendências , Serviços de Integração Docente-Assistencial/normas , Docentes/normas , Docentes/organização & administração , Análise Fatorial , Psicologia Educacional/classificação , Psicologia Educacional/métodos , Psicologia Educacional/organização & administração , Universidades/normas
12.
Cuad. Hosp. Clín ; 41(1): 7-14, 1995. tab
Artigo em Espanhol | LILACS | ID: lil-157899

RESUMO

Nuestro proposito tiene una doble finalidad, en primer lugar hacer un analisis de los factores que contribuyen en la funcion respiratoria de niños expuestos a diferentes ambientes ecologicos, altura y tropico y de diferente estado nutricional; en segundo lugar un estudio comparativo que permite ratificar los valores de referencia establecidos con el fin de efectuar una evaluacion funcional en patologia respiratoria infantil. Se comparan los volumenes pulmonares de cuatro grupos de niños en edad prepuberal habitantes de altura (LA PAz 3700 m sobre el nivel del mar, presion barometrica: 495 mmHg y de tierras bajas (Santa Cruz, 420 msnm, presion barometrica: 760 mmHg). El grupo de la altura GA (N=67) fue estudiado en el Instituto Boliviano de Altura (I.B.B.A), y dividido en dos subgrupos GA1 que corresponde a niños de nivel socioeconomico de nivel alto (N=23) y GA2 de nivel socioeconomico bajo (N=44). El grupo de tierras bajas GB (N=71) fue estudiado en CENETROP, y dividido en dos subgrupos GB1 formados por niños de nivel socioeconomicos altos (N=43) y GB2 de nivel socioeconomico bajo (N=28).


Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Estado Nutricional/fisiologia , Respiração/fisiologia
13.
La Paz; INSTITUTO BOLIVIANO DE BIOLOGIA DE ALTURA; 1992. 179 p. ilus, tab, graf.
Monografia em Espanhol | LIBOCS, LIBOSP | ID: biblio-1307153

RESUMO

Es absolutamente necesario reconocer el invalorable apoyo administrativo financiero que la Universidad Mayor de San Andres a través del Honorable Consejo Facultativo de la facultad de medicina, brinda al I.B.B.A para cumplir con las tareas de investigación , dociencia e interelacion social como lo establece en su estatuto orgánico


Assuntos
Humanos , Academias e Institutos , Biologia , Doença da Altitude , Organização e Administração , Relação Estrutura-Atividade
14.
Rev. ADM ; 48(2): 85-94, mar.-abr. 1991. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-106498

RESUMO

La elección de la investigación sobre crecimiento y desarrollo craneofacial en niños mexicanos, fue con base a la falta de información nacional en este rubro y como parte fundamental del contenido del módulo "crecimiento y desarrollo en el escolar" de la Universidad Autónoma Metropolitana-Xochimilco, cuya hipótesis de trabajo consistió en que "las alteraciones de crecimiento y desarrollo cranoefacial de la población infantil mexicana, entre lo 6 y 12 años de edad en el área de Xochimilco, son causados por deficiencias nutricionales, retraso en la erupción de la segunda dentición y la maloclusión dental", la cual fue comprobada en su totalidad al realizar un trabjao de campo con el estudio de 100 niños de características faciales mexicanas, en los cuales se incluyeron estudios cefalométrios y los cuales permitieron determinar el patrón de crecimiento dentofacial. Este estudio fue corroborado integralmente mediante el seguimiento de 40 niños a los 4 años posteriores del estudio inicial


Assuntos
Cefalometria , Crânio/crescimento & desenvolvimento , Face/crescimento & desenvolvimento , Má Oclusão/epidemiologia , Alimentação Escolar , Fatores Socioeconômicos
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